Some patients notice reduced pain and improved function within a few days. Others may take up to 2–3 weeks as tissue healing progresses.

Advanced regenerative therapy for chronic foot and ankle conditions by Dr. Solomon
Synapep Therapy is one of the latest advancements we offer in regenerative foot and ankle medicine. Under the expert care of Dr. Solomon, this cutting-edge treatment utilizes bioactive peptides to stimulate tissue repair, reduce inflammation, and support healing without the need for surgery or extended recovery.
Synapep Therapy is a next-generation peptide-based injection treatment designed to target soft tissue damage, nerve pain, joint inflammation, and chronic musculoskeletal conditions. It harnesses the natural signaling molecules known as peptides, small chains of amino acids that act as messengers within the body, to accelerate healing at the cellular level.
These bioactive peptides influence cell behavior by regulating inflammatory pathways, enhancing collagen synthesis, promoting tissue regeneration, and improving cellular communication. Synapep injections are especially promising for patients who have not responded to conservative treatment options such as physical therapy, rest, or corticosteroid injections.
Dr. Solomon uses Synapep Therapy to manage and support recovery from a wide range of podiatric conditions:
The peptides used in Synapep therapy work to stimulate a natural healing cascade that reduces pain and inflammation, while encouraging stronger and more resilient tissue formation.
The body naturally produces peptides to regulate healing, immune response, and cellular repair. Synapep Therapy enhances these natural processes by introducing additional concentrated peptides directly into the affected tissues. This boosts the body’s healing potential in targeted areas.
Key actions of Synapep Therapy:
These combined actions help restore normal tissue structure and function without the need for invasive surgical procedures.
Dr. Solomon performs a comprehensive evaluation of your foot or ankle condition. This includes a physical exam, review of imaging if necessary, and discussion of your treatment goals and medical history.
If Synapep Therapy is appropriate, Dr. Solomon will explain the injection procedure and expected outcomes. The injection site will be cleaned and prepped, and a local anesthetic may be applied to ensure comfort.
The Synapep solution is injected precisely into the target area—whether it’s a joint, tendon, ligament, or nerve-affected site. Ultrasound guidance may be used to increase precision.
There is little to no downtime. Most patients return to daily activity the same day, although strenuous activity may be limited for a few days. Some may experience temporary soreness at the injection site, which typically resolves within 24 to 72 hours.
The number of Synapep injections needed varies depending on the condition being treated, severity of damage, and the patient’s overall health.
Dr. Solomon will customize a treatment plan that reflects your healing response and desired outcomes. Booster treatments may also be considered for long-term management.
This therapy is ideal for individuals seeking a non-surgical solution to chronic or acute soft tissue and nerve injuries. Good candidates include:
Contraindications may include:
Dr. Solomon will determine candidacy during your initial visit.
Synapep Therapy differs from treatments like PRP (Platelet-Rich Plasma) and amniotic fluid injections by using targeted peptides rather than relying on growth factors derived from blood or tissue samples. Its key benefits include:
While PRP and amniotic fluid are also valuable, Synapep offers a unique, often faster-acting alternative, especially when pain or inflammation is persistent.
To maximize the benefits of Synapep, Dr. Solomon may recommend adjunct therapies:
Each plan is tailored to the patient’s condition, lifestyle, and long-term goals.
Patients choosing Synapep Therapy at Solomon Aesthetic Podiatry benefit from:
Dr. Solomon’s background in limb preservation means each treatment is backed by medical precision and a deep understanding of functional biomechanics.
Solomon Aesthetic Podiatry is located in the heart of Beverly Hills at 433 North Camden Drive, Suite 610. We are open Monday through Sunday from 9:00 AM to 9:00 PM, offering extended hours for your convenience. Call us today to book your consultation or learn more about Synapep Therapy for foot and ankle conditions. Experience the benefits of advanced regenerative care in a modern, patient-centered setting.
Call us now: (310) 876-5744
Start your recovery with innovative treatment that works naturally with your body. Discover the power of Synapep Therapy with Dr. Solomon.

Some patients notice reduced pain and improved function within a few days. Others may take up to 2–3 weeks as tissue healing progresses.
Side effects are rare and typically mild. Some patients experience brief soreness or swelling at the injection site. Serious complications are extremely rare.
Yes. It is often used alongside custom orthotics, physical therapy, bracing, or other regenerative treatments like PRP or laser therapy.
Cortisone reduces inflammation but does not heal tissue and may weaken structures with repeated use. Synapep promotes healing and structural regeneration.
Most patients find the injection very tolerable. A local anesthetic is often used to minimize discomfort.
Wear comfortable clothing and bring a list of current medications. Avoid NSAIDs for several days before and after treatment, as they may interfere with the healing process.
If Synapep does not provide sufficient relief, Dr. Solomon will explore alternative options such as laser therapy, amniotic injections, or minimally invasive surgery.
Meet with Dr. Solomon for a complimentary 15-minute consultation to discuss your concerns and goals. Discover personalized, expert podiatric care focused on comfort, precision, and long-term results.